만성편두통 치료를 위한 측두 부위의 보툴리눔 독소 주사 자입점 제시
A proposal of injection points of botulinum toxin into temporal region
김영건, 배정희, 김성택,
소속 상세정보
김영건 ( Kim Young-Gun ) - 연세대학교 치과대학 구강내과학교실
배정희 ( Bae Jung-Hee ) - 연세대학교 치과대학 구강생물학교실
김성택 ( Kim Seong-Taek ) - 연세대학교 치과대학 구강내과학교실
KMID : 1004520170330010001
Abstract
Botulinum toxin (BoNT) injections have been used not only in the field of cosmetic surgery such as forehead and eye wrinkle treatment but also in the treatment of chronic migraine, dystonia, spasticity, temporomandibular disorders (TMD). BoNT injections are the only approved therapies to date for prophylactic treatment of chronic migraine patients. Unlike the previously known paralysis of motor neurons, the mechanism of action for migraine is to block the release of non-cholinergic neurotransmitters such as substance P, CGRP, and glutamate, which are associated with peripheral sensitization and neurogenic inflammation in the sensory nerve, it is hypothesized that the signal is blocked. This review focuses on the analgesic effects of BoNT and suggests the direction for the development of injection methods for chronic migraine patients.
키워드
보툴리눔 독소; 통증; 편두통; 만성두통
botulinum toxin; pain; migraine; chronic headache
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